Dermatitis is an acute inflammation of the skin caused by exogenous or endogenous factors. Unlike eczema, a chronic recurrent disease with polymorphism of rash and polyetiology of factors, dermatitis has a shorter course (disappears after elimination of factors) and less polymorphic manifestation. Some people get rid of dermatitis with this drug: https://pillintrip.com/medicine/lepicortinolo.
Etiology and classification
Allergic dermatitis is subdivided into: 1) contact allergic (from exposure to exoallergens – pollen, household, epidermal, food, insect components); 2) toxic-allergic (toxidermia, occurring more often with parenteral administration of haptens, accompanied by marked dysmetabolic changes due to systemic skin lesions); 3) atonic (combination of atonic respiratory diseases with chronic recurrent skin lesions – eczema); 4) fixed erythema.
The development of allergic dermatitis is promoted by hereditary predisposition, endocrinopathies and other intraorganic changes. Among sensitizers in the development of AD the most important are various haptens in the form of drugs. In industrial conditions dinitrochlorobenzene, phenol formaldehyde, epichlorohydrin, turpentine, salts of chromium, nickel, titanium, mercury, acrylonitrate components, ursol and others can cause AD.
In contact allergic dermatitis monovalent sensitization, reverse development upon elimination of the allergen is noted. Areas of hyperemia with separate elements – papules or vesicles – at the places of contact with the allergen are observed. The concentration of allergen is important in contact allergic dermatitis, while repeated contact results in dermatitis with minimal concentrations of allergen.
Clinical manifestations of toxidermia are polymorphic, disseminated rashes in the form of continuous hyperemia, edema of the skin itself, diffuse distribution of various elements – papules or erythematous rosaceous rashes accompanied by intense itching, general reactions (increase in body temperature, redistributive leukocytosis).
Atonic dermatitis is characterized by a relapsing chronic course, polymorphism of rashes, symmetrical arrangement of elements on the background of atonic respiratory changes or food, insect allergies.
Fixed erythema appears on the skin or mucous membranes in the form of one or two spots with sharply delineated edges up to 2-8 cm in size. The peripheral area of the spots may be somewhat elevated.
In contact with chemicals in industrial conditions, simple contact dermatitis may develop, which often leads to contact allergic dermatitis, followed by possible development of toxic-allergic dermatitis with multisystemic manifestations. In case of contact with medications, at first it can be contact allergic dermatitis (hands, neck, face) or allergic rhinitis (in the places of greatest contact with allergens in the form of aerosols). These changes can transform into a toxic-allergic (in the form of toxidermia) or autoimmune (Lyell or Stevens-Johnson syndrome) reaction.