Features of the disease course when HIV and Hepatitis C occur simultaneously

HIV and hepatitis C form a rare link in immunodeficiency syndrome, which induces serum aminotransferase growth. Studies of immunologists and hepatologists reduce the level of body resistance to external factors leads to liver dysfunction.

Another feature of diseases are the same risk groups:

  • marginalized people (homeless people, drug addicts, etc.),
  • health workers,
  • donors,
  • patients who were transfused,
  • homosexuals,
  • children of infected parents.

Warning! There is a perception, but not confirmed, that the presence of co-infection accelerates the transition of HIV into AIDS.

At the same time, HIV and hepatitis are worse tolerated by people than usual diseases, and life expectancy and quality of life deteriorates without effective treatment.

Hepatitis C course of action against HIV infection

Hepatitis C development accelerates drugs prescribed for HIV antiretroviral therapy. The body’s defensive reactions are worsening, which leads to hepatitis becoming chronic.

If HIV is diagnosed with a child’s parents, the child is not only more likely to transmit the virus, but also to acquire new hepatitis and herpes.

Diagnosis

Features of the disease course when HIV and Hepatitis C occur simultaneously

The initial stages of HIV and hepatitis are asymptomatic – the first signs appear 6 months to 1 year later (depending on the state of the immune system). In case of coinfection, the symptoms are manifested earlier, but in order to make an accurate diagnosis it is necessary to take a test.

To diagnose hepatitis, the doctor prescribes a referral for tests:

  • blood and urine,
  • biochemistry,
  • diagnostics of B and C type viruses through PCR,
  • Ultrasound of internal organs.

Diagnostics of HIV is made at the delivery of venous blood. The main methods are ELISA (checking the biomaterial for antibodies) and PCR (viral load determination, confirmation of a positive ELISA result).

Medical manipulations

Hepatitis C and HIV are both complicating treatment, but the only way to fight these infections is to take antiretroviral drugs. No medical manipulation can reduce the viral load and restore the liver.

However, if hepatitis C develops rapidly against the backdrop of HIV, it is recommended that hepatitis A and B be inoculated.

In addition, it is important in treatment:

  • Keeping to a diet. The number of meals – at least 2-3 times a day, small portions, a balanced diet.
  • Light load. Walking, yoga, swimming or cycling will improve your general health.
  • Quit alcohol and smoking. Allows you to reduce the risk of liver disease progression.

Antiretroviral drugs

Features of the disease course when HIV and Hepatitis C occur simultaneously

Interferon and ribavirin are the main drugs for hepatitis C treatment (including chronic form). Only when taken at the same time, they can destroy the virus and improve the body’s defenses.

Interferon is a protein formed in the body to fight infections. When it gets into the gastrointestinal tract, it is destroyed, so it is injected subcutaneously. Ribavirin is aimed at strengthening the action of interferon.

Among the prescribed antiretroviral drugs:

  • Zidovudin. If hepatitis C is treated simultaneously, it is recommended to replace it with another drug from the NIOT group (e.g., phosphazide).
  • Didanosine. However, it is prohibited for cirrhosis of the liver. It is contraindicated to take the drug with stavudin + ribavirin.
  • Efavirenz. It can cause mental disorders, so take with Peg-IFN carefully.
  • Protease inhibitors.

Related Post

XtampzaXtampza

Posology and method of administration. Adults over 18 years: Oxycodone solution should be taken at 4-6 hourly intervals. The dosage is dependent on the severity of the pain, and the